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Advanced Engineering Science

Gongcheng Kexue Yu Jishu/Advanced Engineering Science
Journal ID : AES-13-06-2025-844

Abstract : Alzheimer’s disease (AD) is a progressive neurode- generative condition that features loss of brain volume, loss of neurons, and deposition of amyloid and tau proteins resulting in dementia and cognitive decline. Since AD evolves 8–15 years before the development of overt symptoms and is not treatable, timely diagnosis is imperative to slow down the progression of the disease and enhance patient outcomes. The objective of this research is to classify Alzheimer’s disease stages using deep learning on the OASIS dataset. The model categorizes subjects into four groups: Non-Demented, Very Mild Demented, Mild Demented, and Moderate Demented. Transfer learning is employed, and ResNet-50 as a feature extraction base model and a custom CNN as a classifier. The input has major neuroimaging biomarkers that include hippocampal volume, cortical thickness, and ventricle volume, which improve the model’s diagnostic capability. The use of pre-trained feature extraction with task- specific fine-tuning yields precise and efficient classification by the proposed method. The project assists in early diagnosis and accurate staging of Alzheimer’s disease, facilitating improved treatment and management practices..
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Gongcheng Kexue Yu Jishu/Advanced Engineering Science
Journal ID : AES-13-06-2025-843

Abstract : This paper explores the application of machine learning algorithms in predicting the compressive strength of high-performance concrete (HPC), a critical aspect of ensuring structural integrity in modern construction. Various machine learning models—such as XGBoost, K-nearest neighbors (KNN), Decision Tree, and Random Forest—were evaluated to predict HPC strength with high accuracy. The study compares the performance of these models using metrics like R², MAE, and RMSE to identify the most effective approach. Results indicate that XGBoost outperformed other models like decision Tree KNN and Random Forest. Feature importance analysis highlighted key factors influencing HPC strength, such as age, cement, and water-to-cement ratio. These findings emphasize the potential of machine learning in improving quality control for HPC and optimizing mix design processes. Future work will explore the integration of environmental factors and advanced hybrid models to further enhance prediction accuracy..
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