The Batang—Mangkang section of the G4218 highway is located in the transition zone from the Jinsha River Valley to the plateau, and facing with strong neotectonic activities, broken rock masses and frequent geological disasters. Therefore, the construction and maintenance of the highway in this region are of huge difficulties. Traditional ground geological survey methods face many difficulties in highway route selection, disaster assessment and stability analysis, etc. Combining the optical remote sensing interpretation of geological hazard points with deformation observation by InSAR technology, it is expected that the geological hazard points in this region can be investigated quickly, accurately and efficiently, and reveal their development and distribution rules of geological disaster points.Under the special geological conditions of the high mountains and valleys of the Qinghai–Tibet Plateau, the common types of geological disasters in the region were summarized, and the method of integrated highway remote sensing identification was put forward based on the study of the characteristics of regional disasters and remote sensing technology. Using this method, we carried out disaster surveys on the Batang—Mangkang section, with full knowledge of optical remote sensing visual interpretation technology and InSAR technology, supplemented by field geological survey, GIS spatial analysis, engineering geological analogy , etc. The conclusions of this article are as follows: 1) A total of 670 geological disasters were interpreted by optical visual remote sensing in the study area,and InSAR technology combined with four kinds of SAR data interpreted 220 active geological disasters; 2) The development rules of different types of geological disasters in the study area varied greatly with the change of topographic features, geological conditions and geological disasters and other influencing factors. There were differences in spatial distribution and formation lithology of geologic hazard using the optical remote sensing or InSAR technology; 3) According to the comparative analysis based on the field work, it was concluded that the interpretation results of optical remote sensing and InSAR had a certain relationship with the interpretation methods, imaging conditions of the images and the activity of landslide. The two methods cannot be used for mutual inspection directly;4) The use of comprehensive remote sensing technology was universal in the highway construction of the high mountain valley of the Qinghai–Tibet Plateau. It made full use of the complementarity of optical remote sensing interpretation technology and InSAR deformation observation technology. On the basis of saving time and cost, this method can have a more comprehensive and accurate understanding of the development of regional geological disasters.